Methods for Treating Conditions Associated with MASP-2 Dependent Complement Activation

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United States of America Patent

APP PUB NO 20240343830A1
SERIAL NO

18628104

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Abstract

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In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a human subject suffering from TMA associated with hematopoietic stem cell transplant. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation.

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Patent Owner(s)

Patent OwnerAddress
WILMINGTON SAVINGS FUND SOCIETY FSB AS COLLATERAL AGENT500 DELAWARE AVENUE 11TH FLOOR WILMINGTON DE 19801

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Demopulos, Gregory A Mercer Island, US 169 2686
Dudler, Thomas A Bellevue, US 9 1
Schwaeble, Hans-Wilhelm Cambridge, GB 76 652

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