ULTRASENSITIVE MOLECULAR DETECTION VIA HYBRIDIZATION CHAIN REACTION
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United States of America Patent
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Issued Date -
Oct 10, 2024
app pub date -
Apr 15, 2024
filing date -
Apr 4, 2023
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Abstract
The present application relates to hybridization chain reaction (HCR). In particular, compositions and methods are presented for ultrasensitive molecular detection using HCR signal amplification. Some embodiments and methods involve cooperative probe junctions, reporter-labeled probes, and nonlinear HCR signal amplification.
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