ANTIGEN-BINDING POLYPEPTIDES DIRECTED AGAINST CD38
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United States of America Patent
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Issued Date -
Oct 10, 2024
app pub date -
Jun 24, 2024
filing date -
Nov 10, 2015
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Abstract
Methods of targeting a CD38-expressing cell for treatment of at least one disease, disorder or condition that is associated with CD38. Polypeptides specifically binding to CD38 which are therefore suitable for the diagnosis and for the therapeutic and prophylactic treatment of diseases which are characterized by increased CD38 expression. Conjugates and pharmaceutical compositions comprising the polypeptides are disclosed as well. Use of such polypeptides in methods for the detection of CD38 and/or CD38-expressing cells in a biological sample. A process for the purification and concentration of CD38 and/or CD38-expressing cells in which the antigen-binding polypeptides are used are also described.
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- A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
- C12Q:MEASURING OR TESTING PROCESSES INVOLVING ENZYMES O....
- C12N:MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF
- G01N:INVESTIGATING OR ANALYSING MATERIALS BY DETERMININ....
- A61P:THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDI....
- C07K:PEPTIDES
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