SYNTHESIS OF COVALENT PROTEIN DIMERS THAT CAN INHIBIT MYC-DRIVEN TRANSCRIPTION

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United States of America Patent

APP PUB NO 20240336649A1
SERIAL NO

18572247

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Abstract

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The disclosure relates to covalent protein dimers of MYC, MAX, and Omomyc; pharmaceutical compositions comprising the covalent protein dimers; methods of making the covalent protein dimers; and methods of treating disorders associated with MYC dysregulation (e.g., cancer) with the covalent protein dimers.

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Patent Owner(s)

Patent OwnerAddress
MASSACHUSETTS INSTITUTE OF TECHNOLOGY77 MASSACHUSETTS AVENUE CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BOIJA, ANN CAMBRIDGE, US 4 3
BUCHWALD, STEPHEN LEFFLER NEWTON, US 1 0
HAWKEN, SUSANA WILSON CAMBRIDGE, US 1 0
JBARA, MUHAMMAD CAMBRIDGE, US 1 0
KLEIN, ISAAC CAMBRIDGE, US 4 3
LI, CHARLES HAN CAMBRIDGE, US 1 0
LOAS, ANDREI CAMBRIDGE, US 4 0
PENTELUTE, BRADLEY L REVERE, US 48 222
POMPLUN, SEBASTIAN CAMBRIDGE, US 5 0
RODRIQUEZ, JACOB JOSHUA LEE SOMERVILLE, US 1 0
SCHISSEL, CARLY KATHERINE CAMBRIDGE, US 1 0

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