NOVEL SALT OF 2-AMINO-2-(2-(1-DECYL-1H-1,2,3-TRIAZOL-4-YL)ETHYL)PROPANE-1,3-DIOL, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME

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United States of America Patent

APP PUB NO 20240336578A1
SERIAL NO

18688333

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Abstract

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The present invention relates to a novel salt of 2-amino-2-(2-(1-decyl-1H-1,2,3-triazol-4-yl)ethyl)propane-1,3-diol, and a pharmaceutical composition containing same. In the results of a comparison with hydrochloride salt of 2-amino-2-(2-(1-decyl-1H-1,2,3-triazol-4-yl)ethyl)propane-1,3-diol and the other salts thereof, the novel salt of 2-amino-2-(2-(1-decyl-1H-1,2,3-triazol-4-yl)ethyl)propane-1,3-diol, according to the present invention, exhibits excellent effects in all of low hygroscopicity, standard stock solution stability, photostability, oxidation stability, pH-dependent stability, solubility and the like. The pharmaceutical composition, of the present invention, containing the novel salt as an active ingredient, can be effectively used for preventing or treating multiple sclerosis, ischemic stroke, focal segmental glomerulosclerosis (FSGS), inflammatory bowel disease, interstitial fibrosis and tubular atrophy (IFTA) or alopecia areata (AA).

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Patent Owner(s)

Patent OwnerAddress
NEXTGEN BIOSCIENCE CO LTDSAMPYEONG-DONG PANGYO SEVEN VENTURE VELLY2 3FL ELENTEC-DONG 17 PANGYO-RO 228BEON-GIL BUNDANG-GU SEONGNAM-SI GYEONGGI-DO 13487

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
KIM, Eunjeong Seongnam-si, Gyeonggi-do, KR 19 282
LEE, Bongyong Seoul, KR 32 201
PARK, Yanghae Seoul, KR 1 0

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