GENOTYPE-SPECIFIC METHODS AND SYSTEMS FOR TREATMENT OF NEURODEGENERATIVE DISEASE
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United States of America Patent
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Issued Date -
Oct 10, 2024
app pub date -
Apr 3, 2024
filing date -
Apr 4, 2023
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Abstract
The present disclosure provides methods of treatment of neurodegenerative disease in subjects in need thereof. A therapeutically effective dose of combination of a suitable mast cell stabilizer and NSAID may be administered to suitable subjects, wherein the suitability of a subject is determined by subject genotype. In certain embodiments, the combination therapy may comprise a combination of a cromolyn homolog salt and an NSAID, and suitable subjects are persons who are not carriers APOE ε4 variant of the APOE gene.
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