SYSTEMS AND METHODS FOR FLUORESCENCE MICROSCOPY CHANNEL CROSSTALK MITIGATION
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United States of America Patent
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Issued Date -
Oct 3, 2024
app pub date -
Mar 31, 2023
filing date -
Mar 31, 2023
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Abstract
Methods and system are provided herein for crosstalk mitigation, such as the removal of crosstalk interference from a microscopy image signal to recover an intended image from the image signal. In one example, a method includes determining a weighted interference signal of a microscopy image by determining a weighting constant of the weighted interference signal that provides a minimum variance, removing the weighted interference signal from an overall signal, and determining the intended image signal based on removal of the weighted interference signal from the overall signal.
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