APELIN POLYPEPTIDES
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United States of America Patent
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Issued Date -
Oct 3, 2024
app pub date -
Jun 11, 2024
filing date -
Jun 10, 2014
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Abstract
The invention provides modified apelin polypeptides having increased stability, circulating half-life, and/or potency relative to the native apelin-13 polypeptide. Compositions comprising the modified apelin polypeptides and methods of using the polypeptides for treating cardiac disorders, such as heart failure, are also disclosed.
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