FUSED TETRACYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE

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United States of America Patent

APP PUB NO 20240327434A1
SERIAL NO

18571909

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Abstract

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The present disclosure relates to a fused tetracyclic compound, a preparation method therefor and an application thereof in medicine. Specifically, the present disclosure relates to a fused tetracyclic compound as shown in general formula (I), a preparation method therefor, a pharmaceutical composition containing the compound, and use thereof as a therapeutic agent, in particular use thereof in preparation of drugs for inhibiting KRAS G12D. The groups in general formula (I) are as defined in the description.

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Patent Owner(s)

Patent OwnerAddress
SHANGHAI HENGRUI PHARMACEUTICAL CO LTDNO 279 WENJING ROAD ECONOMIC AND TECHNOLOGICAL DEVELOPMENT ZONE MINHANG DISTRICT SHANGHAI 200245
JIANGSU HENGRUI PHARMACEUTICALS CO LTDNO 7 KUNLUNSHAN ROAD ECONOMIC AND TECHNOLOGICAL DEVELOPMENT ZONE LIANYUNGANG JIANGSU 222047 222047

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CHEN, Yang Shanghai, CN 340 2375
DONG, Huaide Shanghai, CN 4 0
HE, Feng Shanghai, CN 194 1424
LI, Xin Shanghai, CN 946 7137
SHEN, Feng Shanghai, CN 57 890
TAO, Weikang Shanghai, CN 112 215

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