COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING VIRAL INFECTIONS

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United States of America Patent

APP PUB NO 20240327339A1
SERIAL NO

18577631

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Abstract

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Probenecid prodrug compounds, and formulations including one or more of probenecid, metabolites and analogs thereof, and prodrugs thereof, and pharmaceutically acceptable salt thereof are provided. Delivery vehicles and pharmaceutical compositions including any of the foregoing are also provided. Methods of using the compounds and compositions to treat viral infections are also provided. In some embodiments, the viral infection is caused by an RNA virus. Particular viruses include, but are not limited to, influenza virus A, influenza virus B, or influenza virus C, respiratory syncytial virus (RSV), coronaviruses, measles virus, mumps virus, Zika virus, and dengue virus. Dosage regimens are also provided.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION INC210 S JACKSON STREET 110 TERRELL HALL ATHENS GA 30602

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Karumanchi, Devi Kalyan Chicago, US 6 3
Martin, David Eugene Shawnee, US 7 23
Murray, Jackelyn Monroe, US 4 1
Tripp, Ralph A Wakinsville, US 37 248

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