ASSEMBLY AND METHOD FOR COMBINED NUCLEIC ACID PURIFICATION AND AMPLIFICATION
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United States of America Patent
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Issued Date -
Oct 3, 2024
app pub date -
Jul 25, 2022
filing date -
Jul 26, 2021
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Abstract
The present invention relates to an assembly and a corresponding method for performing a combined assay of nucleic acid purification and amplification from a biological sample, in particular with regard to prepare a library for next generation sequencing. A unique rotary design of one or more fluidic cards in the assembly allows for moving of biological samples and reagents around the fluidic card(s) based on centrifugal force provided by rotary motion and coupled with an indexing mechanism. By orienting the fluidic card(s) appropriately the fluidic flow can be directed from and to the various chambers on the fluidic card(s) to perform the different assay steps without the need of batching during sample processing.
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