BORATE COMPLEXES OF CHLOROGENIC ACID AND USES THEREOF
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United States of America
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Issued Date -
Oct 3, 2024
app pub date -
Oct 21, 2022
filing date -
Oct 21, 2022
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Abstract
A borate diester of chlorogenic acid is prepared by reacting a solution comprising chlorogenic acid and boric acid in a ratio of at least 2:1 in a superheated water solvent or an aqueous acetonitrile solvent. If aqueous acetonitrile is used as a solvent, the acetonitrile solvent is evaporated to leave a water solution. A product containing the desired borate diester is obtained by freeze-drying or air-drying the water solution. Insufficient levels of boron in a microbiome in a subject in need thereof may be treated by administering the borate diester of chlorogenic acid to the subject.
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