PREFUSION-STABILIZED CHIMERIC HMPV-RSV F PROTEINS

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United States of America Patent

APP PUB NO 20240317810A1
SERIAL NO

18578966

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Abstract

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Provided herein are chimeric hMPV/RSV F proteins. In some aspects, the chimeric hMPV/RSV F proteins exhibit enhanced conformational stability, enhanced thermostability, and/or increased expression. Methods are also provided for use of the chimeric F proteins as diagnostics, in screening platforms, and/or in vaccine compositions.

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Patent Owner(s)

Patent OwnerAddress
BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM201 WEST 7TH STREET AUSTIN TX 78701

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
HSIEH, Ching-Lin Austin, US 22 35
MCLELLAN, Jason Austin, US 24 161

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