ENGINEERED NATURAL KILLER (NK) CELLS AND RELATED METHODS
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United States of America Patent
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Issued Date -
Sep 26, 2024
app pub date -
Jun 30, 2022
filing date -
Jul 1, 2021
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Abstract
Provided herein are engineered Natural Killer (NK) cells deficient in expression of FcRγ chain (g-NK cells), and further comprising a recombinant chimeric antigen receptor (CAR) and compositions thereof. Also provided herein are compositions containing the engineered NK cells and methods of making and using the engineered NK cells.
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