METHODS AND COMPOSITIONS TO DIAGNOSE AND TREAT TAUOPATHIES UTILIZING TRANSCRIPT VARIANTS OF PSEN2

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United States of America Patent

APP PUB NO 20240309371A1
SERIAL NO

18410822

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The current disclosure describes methods and composition for treating and diagnosing tauopathies utilizing transcript variants of PSEN2. Reduction of transcript variants of PSEN2 and/or preservation of canonical splicing can be beneficial in the treatment of tauopathies such as Alzheimer's disease. Methods of diagnosing sporadic Alzheimer's disease are also provided.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF WASHINGTON4545 ROOSEVELT WAY NE SUITE #400 SEATTLE WA 98105

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Course, Meredith Seattle, US 1 0
Valdmanis, Paul Seattle, US 4 2

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