PYRAN DERIVATIVES AS CYP11A1 (CYTOCHROME P450 MONOOXYGENASE 11A1) INHIBITORS

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United States of America Patent

APP PUB NO 20240308989A1
SERIAL NO

18674603

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Compounds of formula (I) wherein R1, R2,R3,R4,R5,R23,R24,L, A and B are as defined in claim 1, or pharmaceutically acceptable salts thereof are disclosed. The compounds of formula (I) possess utility as cytochrome P450 monooxygenase 11A1(CYP11A1) inhibitors. The compounds are useful as medicaments in the treatment of steroid receptor, particularly androgen receptor, dependent diseases and conditions, such as—prostate cancer.

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Patent Owner(s)

Patent OwnerAddress
ORION CORPESPOO FINLAND

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Din, Belle David Espoo, FI 20 15
Mäkelä, Mikko Espoo, FI 16 48
Passiniemi, Mikko Helsinki, FI 5 3
Pietikäinen, Pekka Espoo, FI 11 3
Rummakko, Petteri Siuntio, FI 20 22
Tiainen, Eija Espoo, FI 16 17
Vaismaa, Matti Espoo, FI 10 4
Wohlfahrt, Gerd Helsinki, FI 28 129

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