SUBUNIT VACCINE DELIVERY PLATFORM FOR ROBUST HUMORAL AND CELLULAR IMMUNE RESPONSES

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United States of America Patent

APP PUB NO 20240307518A1
SERIAL NO

18365815

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Abstract

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The present invention relates to a probiotic cell transformed with a construct suitable to overexpress and display on the surface of the probiotic cell a fusion protein comprising at least a portion of a transport protein coupled to at least a portion of one or more antigenic proteins or peptides. Probiotic-derived vesicles displaying this fusion protein as well as methods of inducing an immune response using the probiotic cells or vesicles are also disclosed.

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Patent Owner(s)

Patent OwnerAddress
UNIV CORNELL395 PINE TREE ROAD SUITE 310 CCTEC ITHACA NY 14850 14850

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
DELISA, Matthew Ithaca, US 24 172
HUANG, Chung-Jr Newbury Park, US 16 31
MENDEZ, Susana Silver Spring, US 7 61
PUTNAM, David A Ithaca, US 23 440
ROSENTHAL, Joseph Ithaca, US 8 40

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