ANTI-HENIPAVIRUS MONOCLONAL ANTIBODY HAVING BROAD SPECTRUM NEUTRALIZATION ACTIVITY AND USE THEREOF

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United States of America Patent

APP PUB NO 20240294614A1
SERIAL NO

18005979

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Abstract

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Provided is an anti-Henipavirus monoclonal antibody having broad spectrum neutralization activity, wherein the antibody comprises a macaque variable region and a human constant region. The antibody of the present invention has good binding activity to both Nipah virus glycoprotein G and Hendra virus glycoprotein G, can effectively neutralize Nipahpseudovirus and Hendra pseudovirus, and can be used for preparing drugs for treating Henipavirus diseases.

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Patent Owner(s)

Patent OwnerAddress
ACADEMY OF MILITARY MEDICAL SCIENCE PLA20 DONGDAJIE STREET FENGTAI DISTRICT BEIJING 100071

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Wei Beijing, CN 2011 24064
Chen, Yi Beijing, CN 458 3558
Chi, Xiangyang Beijing, CN 3 0
Dong, Yunzhu Beijing, CN 2 0
Fan, Pengfei Beijing, CN 5 0
Fang, Ting Beijing, CN 33 45
Hao, Meng Beijing, CN 6 29
Li, Jianmin Beijing, CN 209 4291
Li, Yaohui Beijing, CN 23 234
Liu, Shuling Beijing, CN 7 233
Liu, Yujiao Beijing, CN 7 0
Song, Xiaohong Beijing, CN 90 2360
Yu, Changming Beijing, CN 6 3
Zhang, Guanying Beijing, CN 4 0

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