NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF

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United States of America Patent

APP PUB NO 20240293567A1
SERIAL NO

18642667

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Desired is development of novel CDN derivatives having STING agonist activity; and a therapeutic agents and/or therapeutic methods using the novel CDN derivatives for diseases associated with STING agonist activity. Further desired is development of a therapeutic agents and/or therapeutic methods capable of delivering the novel CDN derivatives specifically to targeted cells and organs for diseases associated with STING agonist activity. The present invention provides novel CDN derivatives having potent STING agonist activity, and antibody-CDN derivative conjugates including the novel CDN derivatives.

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Patent Owner(s)

Patent OwnerAddress
DAIICHI SANKYO COMPANY LIMITED3-5-1 NIHONBASHI HONCHO CHUO-KU TOKYO 1038426 ?1038426

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
ARAI, Masami Tokyo, JP 19 146
HARA, Kyoko Tokyo, JP 3 3
ISHIZAKI, Masayuki Tokyo, JP 17 809
KOBAYASHI, Hiroyuki Tokyo, JP 792 9078
TABUCHI, Toshiki Tokyo, JP 2 3
TSUDA, Toshifumi Tokyo, JP 5 6
WADA, Teiji Tokyo, JP 5 5
WATANABE, Hideaki Tokyo, JP 197 3217

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