COMPOUND AND METHOD FOR TREATING CHEMOTHERAPY-RELATED GASTROINTESTINAL SIDE EFFECTS
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Sep 5, 2024
app pub date -
Jun 9, 2022
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Jun 10, 2021
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A method for treating chemotherapy-related gastrointestinal side effects, in particular, relating to use of a CDK inhibitor in preparation of a drug. The drug is used for preventing, alleviating and/or treating the chemotherapy-related gastrointestinal side effects on a subject. The CDK inhibitor comprises a CDK1 inhibitor, a CDK2 inhibitor, a CDK3 inhibitor, a CDK4 inhibitor, a CDK5 inhibitor, a CDK6 inhibitor, a CDK7 inhibitor, a CDK 8 inhibitor, and/or CDK9 inhibitor. A chemotherapeutic agent may be selected from fluorouracil, oxaliplatin, topotecan, irinotecan, tetrahydrofolate, docetaxel, and the like. The gastrointestinal side effects comprise diarrhea, constipation, and the like.
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