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Abstract

The disclosure provides evaluation of the spatial and topical repellent and knockdown activities of benzoates against blood-sucking arthropods and compared with DEET using both high-throughput in vitro screening tests and arm-in-cage in vivo assays in the laboratory. Tested alone or in blends were methyl benzoate (MB), ethyl benzoate (EB), vinyl benzoate (VB), n-propyl benzoate (nPrB), n-butyl benzoate (nBB), benzyl benzoate (BB), methyl 2-chlorobenzoate (M2CB), methyl 2-nitrobenzoate (M2NB), iso-butyl benzoate (iBB), n-pentyl benzoate (nPeB), n-hexyl benzoate (nHB), methyl 3-methylbenzoate (M3MB), iso-pentyl benzoate (also called iso-amyl benzoate) (iPeB), iso-propyl benzoate (iPrB), methyl 2-methoxybenzoate (M2MOB), ethyl 2-methoxybenzoate (E2MOB), ethyl 4-methoxybenzoate (E4MOB), methyl anthranilate (MA), Methyl 2-(aminosulfonyl)benzoate (M2ASB), n-butyl anthranilate (nBA), methyl 3-nitrobenzoate (M3NB), methyl 4-nitrobenzoate (M4NB), ethyl 3-aminobenzoate (E3AB), allyl anthranilate (AA), methyl 2-methylbenzoate (M2MB), methyl 3-methoxybenzoate (M3MOB), ethyl anthranilate (EA), methyl N-methylanthranilate (MMA), methyl N,N-dimethylanthranilate (MDMA), iso-butyl anthranilate (iBA), methyl N-acetylanthranilate (MAcA), methyl N-formylanthranilate (MFA), ethyl N-formylanthranilate (EFA), n-Propyl N-formylanthranilate (nPrFA), or n-Butyl N-formylanthranilate (nBFA).

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