BISPECIFIC ANTIBODY
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United States of America Patent
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Issued Date -
Aug 29, 2024
app pub date -
Apr 30, 2024
filing date -
Feb 9, 2018
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Abstract
A bispecific antibody which is capable of specifically binding to PD-1 and CD3 is disclosed. The bispecific antibody is suitable for preventing, suppressing symptom progression or recurrence of, and/or treating autoimmune diseases. Also disclosed is a formulation which can reduce occurrence of adverse infusion reactions or adverse reaction called cytokine release syndrome. The bispecific antibody has the feature to allow interaction between PD-1 and PD-L1 as its ligand, contributes enhancement or duration of its effects.
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