TRICYCLIC COMPOUND USED AS GPR84 ANTAGONIST
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United States of America Patent
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Aug 29, 2024
app pub date -
Jun 21, 2022
filing date -
Jun 21, 2021
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Abstract
The present invention relates to a tricyclic compound used as a GPR84 antagonist, and in particular relates to a tricyclic compound having a structure shown in formula I, and tautomers, stereoisomers, hydrates, solvates, pharmaceutically acceptable salts or prodrugs thereof; the definitions of the ring Cy, L1, R1 are as described in the present invention; the tricyclic compound has significant GPR84 antagonism, good pharmaceutical developability and high safety.
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