NOVEL BIFUNCTIONAL HETEROCYCLIC COMPOUND HAVING BTK DEGRADATION FUNCTION VIA UBIQUITIN PROTEASOME PATHWAY, AND USE THEREOF

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United States of America Patent

APP PUB NO 20240285778A1
SERIAL NO

18573904

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Abstract

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The present invention relates to a novel heterocyclic compound and a composition, for preventing or treating a cancer, an autoimmune disease, and an inflammatory disease, comprising same. The novel heterocyclic compound of the present invention is a bifunctional compound having a Bruton's tyrosine kinase (BTK) degradation function via a ubiquitin proteasome pathway, and may be utilized as a composition for preventing or treating a cancer, an autoimmune disease, and Parkinson's disease.

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Patent Owner(s)

Patent OwnerAddress
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY141 GAJEONG-RO YUSEONG-GU DAEJEON 305-343
UBIX THERAPEUTICS INCC-1401 7 BEOBWON-RO 11-GIL SONGPA-GU SEOUL 34114

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
AHN, Jung Min Incheon, KR 9 1
CHO, Sung Yun Daejeon, KR 18 47
HA, Jae Du Daejeon, KR 14 47
HWANG, Jong Yeon Daejeon, KR 16 3
KIM, Han Wool Ansan-si, KR 4 0
KIM, Hyun Jin Daejeon, KR 272 4698
KIM, Pil Ho Daejeon, KR 27 140
LEE, Ho Hyun Siheung-si, KR 12 0
LEE, Song Hee Seoul, KR 11 4
LIM, Ye Seul Seoul, KR 4 0
MOON, Hee Jung Incheon, KR 6 0
PARK, Chi Hoon Daejeon, KR 15 72
PARK, Ji Youn Seongnam-si, KR 7 3
RYU, Je Ho Seongnam-si, KR 15 21
SUH, Beom Seon Seongnam-si, KR 3 0
YOO, Sun Mi Seoul, KR 4 0

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