SOLID DOSAGE FORMS AND DOSING REGIMENS COMPRISING (2R,3S,4S,5R)-4-[[3-(3,4-DIFLUORO-2-METHOXY-PHENYL)-4,5-DIMETHYL-5-(TRIFLUOROMETHYL) TETRAHYDROFURAN-2-CARBONYL]AMINO]PYRIDINE-2-CARBOXAMIDE

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United States of America Patent

APP PUB NO 20240285596A1
SERIAL NO

18566176

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Abstract

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Provided is a solid dispersion of (2R,3S,4S,5R)-4-[[3-(3,4-difluoro-2-methoxy-phenyl)-4,5-dimethyl-5-(trifluoromethyl) tetrahydrofuran-2-carbonyl]amino]pyridine-2-carboxamide (Compound 1), defined as described herein, or a pharmaceutically acceptable salt thereof and a tablet containing the solid dispersion for treating pain. Also disclosed herein is Compound 1 or a pharmaceutically acceptable salt thereof for use in a method of treating pain.

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Patent Owner(s)

Patent OwnerAddress
VERTEX PHARMACEUTICALS INCORPORATED50 NORTHERN AVENUE BOSTON MA 02210

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BENITO, GALLO Paloma Didcot, Oxfordshire, GB 1 0
CHU, Cathy Cambridge, US 5 33
CIRINCIONE, Brenda Boston, US 4 21
CORRELL, Darin J Dover, US 1 0
DELFF, Philip Kaj Harder Watertown, US 1 0
DINEHART, Kirk Raymond Holliston, US 6 193
HAY, Tanya Louise Oxford, Oxfordshire, GB 1 0
JIANG, Licong San Diego, US 7 199
JONES, James B Norfolk, US 20 423
KARKARE, Radhika Framingham, US 5 131
MCCARTY, Katie L Watertown, US 1 0
METZLER, Catherine P Medford, US 1 0
MILLER, Jonathan M Grafton, US 18 401
PETERSON, Mark C Westford, US 3 24
ROOPWANI, Rahul Natick, US 1 0
STAROPOLI, John F Boston, US 1 0

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