DIAGNOSTIC METHOD
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United States of America Patent
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Issued Date -
Aug 22, 2024
app pub date -
Jan 12, 2024
filing date -
Sep 27, 2006
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Abstract
The present invention concerns a method for the detection or monitoring of cancer using a biological sample selected from blood, plasma, serum, saliva, urine from an individual, said method comprising:
- (a) obtaining DNA from the said biological sample;(b) digesting the DNA sample with one or more methylation-sensitive restriction enzymes;(c) quantifying or detecting a DNA sequence of interest after step (b), wherein the target sequence of interest contains at least two methylation-sensitive restriction enzyme recognition sites; and(d) comparing the level of the DNA sequence from the individual to a normal standard, to detect, prognosticate or monitor cancer.
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