Rare Cell Analysis Using Sample Splitting And DNA Tags

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United States of America Patent

APP PUB NO 20240279738A1
SERIAL NO

18463607

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides systems, apparatuses, and methods to detect the presence of fetal cells when mixed with a population of maternal cells in a sample and to test fetal abnormalities, e.g. aneuploidy. The present invention involves labeling regions of genomic DNA in each cell in said mixed sample with different labels wherein each label is specific to each cell and quantifying the labeled regions of genomic DNA from each cell in the mixed sample. More particularly the invention involves quantifying labeled DNA polymorphisms from each cell in the mixed sample.

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Patent Owner(s)

Patent OwnerAddress
VERINATA HEALTH INC800 SAGINAW DRIVE REDWOOD CITY CA 94063

International Classification(s)

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  • 2023 Application Filing Year
  • C12Q Class
  • 2389 Applications Filed
  • 320 Patents Issued To-Date
  • 13.40 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Davis, Ronald W Palo Alto, US 96 3007
Kapur, Ravi Sharon, US 102 6293
Shoemaker, Daniel San Diego, US 34 1437
Stoughton, Roland B The Sea Ranch, US 9 182
Toner, Mehmet Charlestown, US 179 7163

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