Method of Purifying Nucleic Acids Using Modified Solid Phases
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United States of America Patent
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Issued Date -
Aug 8, 2024
app pub date -
Feb 1, 2024
filing date -
Feb 2, 2023
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Abstract
A method of purifying nucleic acids using solid phases that are modified by a blocking reagent to limit the binding area and/or binding site of the solid phases to reduce the binding capacity of the solid phase to the nucleic acids. The starting amount of the nucleic acids exceeds the binding capacity of the solid phase, and the amount of the purified nucleic acid is in a fix amount, not proportional to the starting amount of the nucleic acids.
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