BACILLUS SUBTILIS ZF-1 AND APPLICATION THEREOF IN INHIBITING AFRICAN SWINE FEVER VIRUS
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United States of America Patent
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Issued Date -
Aug 8, 2024
app pub date -
Mar 15, 2024
filing date -
Apr 26, 2022
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Abstract
The Bacillus subtilis ZF-1 and use thereof in inhibiting African swine fever virus are provided. A Bacillus subtilis strain (CCTCC NO: M2022185) is screened and selected from 95 self-preserved strains with an inhibiting effect on African swine fever virus. The strain has a remarkable anti-ASFV effect in vivo and in vitro through anti-infection research at a cell level and an animal body level, can reduce proliferation of the virus in a pig body and damage of ASFV infection to tissues and organs, can effectively control adverse effects of ASFV infection on the body, and can be used for preventing and controlling African swine fever epidemics.
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