Engineered Neural Networks in Tailored Hydrogel Sheaths and Methods for Manufacturing the Same

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United States of America Patent

APP PUB NO 20240252726A1
SERIAL NO

18561507

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Abstract

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In various aspects and embodiments the present disclosure provides a construct comprising a pre-formed neural network, the construct comprising a micro-column comprising an outer sheath comprising a hyaluronic acid (HA) hydrogel, and a core comprising an extracellular matrix (ECM); a plurality of neurons within the micro-column. The present disclosure further provides methods of making and using the same.

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Patent Owner(s)

Patent OwnerAddress
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA3600 CIVIC CENTER BOULEVARD 9TH FLOOR PHILADELPHIA PA 19104
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS810 VERMONT AVENUE NW WASHINGTON DC 20420

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Burdick, Jason A Philadelphia, US 8 86
Chen, H Isaac Penn Valley, US 2 2
Cullen, Daniel Kacy Media, US 14 4
Gordian-Velez, Wisberty J Philadelphia, US 1 0

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