GENE THERAPY CONSTRUCTS AND METHODS FOR TREATMENT OF HEARING LOSS
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United States of America Patent
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Issued Date -
Aug 1, 2024
app pub date -
May 14, 2022
filing date -
May 14, 2021
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Abstract
Disclosed are compositions and methods that may be useful in the treatment and/or prevention of hearing loss caused by genetic mutation of the STRC gene. The compositions and methods disclosed herein use Lentiviral vectors to facilitate delivery of STRC into the inner ear to restore activity of the STRC gene, respectively, promote hair cell survival, prevent further degradation of hearing and/or restore hearing in patients suffering from hearing loss.
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