CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF

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United States of America Patent

APP PUB NO 20240246898A1
SERIAL NO

18489240

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Abstract

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The present invention provides cationic lipids and lipid nanoparticle formulations comprising these lipids, alone or in combination with other lipids. These lipid nanoparticles may be formulated with nucleic acids to facilitate their intracellular delivery both in vitro and for therapeutic applications. The present invention also provides methods of chemical synthesis of these lipids, lipid nanoparticle preparation and formulation with nucleic acids.

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Patent Owner(s)

Patent OwnerAddress
RAMOT AT TEL-AVIV UNIVERSITY LTDP O BOX 39296 TEL-AVIV 6139201

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
PEER, Dan Kiryat Ono, IL 40 182
RAMISHETTI, Srinivas Tel Aviv, IL 6 19

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