A 19-NOR C3,3-DISUBSTITUTED C21-N-PYRAZOLYL STEROID FOR THE TREATMENT OF MAJOR DEPRESSIVE DISORDER

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United States of America Patent

APP PUB NO 20240245711A1
SERIAL NO

18550724

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Abstract

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The present disclosure relates to methods of treating major depressive disorder (MDD) in a subject in need thereof by (i) performing an initial treatment course on the subject comprising administering a therapeutically effective amount of Compound (1), or a pharmaceutically acceptable salt thereof, and (ii) performing 0, 1, or 2 subsequent treatment courses on the subject, wherein each subsequent treatment course comprises administering a therapeutically effective amount of Compound (1), or a pharmaceutically acceptable salt thereof, in response to a recurrence of depression symptoms. The 0, 1, or 2 subsequent treatment courses can be performed over a period of 12 months from the beginning of the initial treatment course.

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Patent Owner(s)

Patent OwnerAddress
SAGE THERAPEUTICS INC215 FIRST STREET CAMBRIDGE MA 02142

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Adiwijaya, Bambang Senoaji Lexington, US 2 0
Doherty, James Bedford, US 33 289
Dunbar, Joi Lisa Needham, US 2 0
Gunduz-Bruce, Handan Lexington, US 12 27
Jonas, Jeffrey Martin Vero Beach, US 4 5
Kanes, Stephen Jay Swathmore, US 25 159
Lasser, Robert Alfonso Brookline, US 7 20

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