FIBRONECTIN BASED SCAFFOLD DOMAIN PROTEINS THAT BIND PCSK9

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United States of America Patent

APP PUB NO 20240239870A1
SERIAL NO

18512487

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Abstract

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The present invention relates to fibronectin based scaffold domain proteins that bind PCSK9. The invention also relates to the use of the innovative proteins in therapeutic applications to treat atherosclerosis, hypercholesterolemia and other cholesterol related diseases. The invention further relates to cells comprising such proteins, polynucleotides encoding such proteins or fragments thereof, and to vectors comprising the polynucleotides encoding the innovative protein.

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Patent Owner(s)

Patent OwnerAddress
BRISTOL MYERS SQUIBB COPRINCETON NJ 08543

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CAMPHAUSEN, Ray Wayland, US 59 1495
Cload, Sharon T Cambridge, US 17 409
Davis, Jonathan H Aubumdale, US 17 396
Denhez, Fabienne M Arlington, US 6 122
Lipovsek, Dasa Cambridge, US 81 1800
Lo, Ching-Hsiung Frederick Pennington, US 12 124
Low, Chee Meng Allston, US 57 587
Miao, Bowman Churchville, US 14 373
Mitchell, Tracy S Andover, US 20 249
Parker, Rex A Titusville, US 12 165
Rakestraw, Ginger C Cambridge, US 15 114
Russo, Katie A Watertown, US 7 122
Saeed-Kothe, Amna West Roxbury, US 13 426
Sitkoff, Doree F Dresher, US 12 182

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