METHOD FOR PROMOTING PROLIFERATION AND PLURIPOTENCY FACTOR EXPRESSION OF STEM CELLS AND COMPOSITION PRODUCED USING THE SAME
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United States of America Patent
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Jul 11, 2024
app pub date -
Jul 26, 2023
filing date -
Jan 11, 2023
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Abstract
A method for promoting proliferation and enhancing expression of pluripotency factors of stem cells and a method for promoting proliferation of cells differentiated from the stem cells are provided in the present disclosure. The methods comprise culturing the stem cells in a medium comprising thrombospondin 1 (TSP1) and left-right determination factor 2 (LEFTY2). The present disclosure also provides a composition comprising a derivative of the stem cells produced by the methods of the present disclosure and a pharmaceutically or cosmetically acceptable carrier.
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