PHARMACEUTICAL COMPOSITION, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
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United States of America Patent
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Issued Date -
Jul 4, 2024
app pub date -
Jul 4, 2022
filing date -
Jul 5, 2021
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Abstract
A pharmaceutical composition, and a preparation method therefor and an application thereof. The pharmaceutical composition comprises a spiro-aryl phosphorus oxide or a pharmaceutically acceptable salt thereof as an active ingredient and a pharmaceutically acceptable carrier. D90 of the spiro-aryl phosphorus oxide or the pharmaceutically acceptable salt thereof is in a range of 40.3 μm to 79.6 μm. The pharmaceutical composition has high content uniformity, a high dissolution rate, and high in-vivo bioavailability, and can be used for treating cancer.
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