ANDROGEN RECEPTOR MODULATORS
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United States of America Patent
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Issued Date -
Jun 20, 2024
app pub date -
Mar 14, 2022
filing date -
Mar 14, 2022
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Abstract
The present disclosure relates to polycyclic (e.g., tetracyclic) androgen receptor (AR) modulators, synthetic methods for preparing such AR modulators, and methods of using such AR modulators to treat an androgen-dependent condition, such as prostate cancer or BPH. Exemplary compounds have quaternary centers at C10 and C13 and a fused cyclic ring comprising C14 and C15.
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