Methods, Systems, and Compositions for Diagnosing Transplant Rejection
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United States of America Patent
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Issued Date -
Jun 13, 2024
app pub date -
Jan 26, 2024
filing date -
Jul 29, 2021
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Abstract
Described herein are methods, compositions, and systems useful for detecting transplant rejection and associated abnormal conditions in solid organ transplant recipients, such as kidney transplant recipients. Methods described herein may involve combined assessment of blood gene expression profiles from an assessment of particular, related mRNA transcript levels and donor-derived cell-free nucleic acids (dd-cfDNA).
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