ANTIBODIES TO PMEL17 AND CONJUGATES THEREOF

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United States of America Patent

APP PUB NO 20240189439A1
SERIAL NO

18454457

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This application discloses anti-PMEL17 antibodies, antigen binding fragments thereof, and antibody drug conjugates of said antibodies or antigen binding fragments conjugated to a GNAQ/GNA11 inhibitor. The invention also relates to methods of treating or preventing cancer using the antibodies, antigen binding fragments, and antibody drug conjugates. Also disclosed herein are methods of making the antibodies, antigen binding fragments, and antibody drug conjugates, and methods of using the antibodies and antigen binding fragments as diagnostic reagents.

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Patent Owner(s)

Patent OwnerAddress
NOVARTIS AGLICHTSTRASSE 35 BASEL 4056

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Burger, Matthew Belmont, US 29 451
D'Alessio, Joseph Anthony Boston, US 12 2
Fleming, Tony Stow, US 17 182
Kunz, Christian Planegg, DE 21 192
Manchado, Robles Eusebio Basel, CH 4 0
Rauniyar, Vivek Cambridge, US 13 14
Waldhuber, Markus Munich, DE 11 6

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