ALDOSE REDUCTASE INHIBITORS AND USES THEREOF

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United States of America Patent

APP PUB NO 20240180907A1
SERIAL NO

18344262

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Abstract

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The present invention relates to novel compounds and pharmaceutical compositions thereof, and methods for promoting healthy aging of skin, the treatment of skin disorders, the treatment of cardiovascular disorders, the treatment of renal disorders, the treatment of angiogenesis disorders, such as cancer, treatment of tissue damage, such as non-cardiac tissue damage, the treatment of evolving myocardial infarction, and the treatment of various other disorders, such as complications arising from diabetes with the compounds and compositions of the invention. Other disorders can include, but are not limited to, atherosclerosis, coronary artery disease, diabetic nephropathy, diabetic neuropathy, diabetic retinopathy, infections of the skin, peripheral vascular disease, stroke, and the like.

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Patent Owner(s)

Patent OwnerAddress
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK412 LOW MEMORIAL LIBRARY 535 W 116TH STREET NEW YORK NY 10027

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
DENG, Shixian White Plains, US 42 137
LANDRY, Donald W New York, US 112 1018
MYLARI, Banavara L East Lyme, US 79 757
RAMASAMY, Ravichandran Ardsley, US 23 199
SCHMIDT, Ann Marie Franklin Lakes, US 64 874
WASMUTH, Andrew Brooklyn, US 19 137

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