Nanopore Arrays for Sequencing Nucleic Acids

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United States of America Patent

APP PUB NO 20240175845A1
SERIAL NO

18391244

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Abstract

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To form a layer separating two volumes of aqueous solution, there is used an apparatus comprising elements defining a chamber, the elements including a body of non-conductive material having formed therein at least one recess opening into the chamber, the recess containing an electrode. A pre-treatment coating of a hydrophobic fluid is applied to the body across the recess. Aqueous solution, having amphiphilic molecules added thereto, is flowed across the body to cover the recess so that aqueous solution is introduced into the recess from the chamber and a layer of the amphiphilic molecules forms across the recess separating a volume of aqueous solution introduced into the recess from the remaining volume of aqueous solution.

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Patent Owner(s)

Patent OwnerAddress
OXFORD NANOPORE TECHNOLOGIES PLCEDMUND HALLEY ROAD GOSLING BUILDING OXFORD SCIENCE PARK OXFORD OX4 4DQ

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Clarke, James Anthony Oxford, GB 75 1512
Reid, Stuart William Oxford, GB 24 414
Reid, Terence Alan Oxford, GB 19 778
Sanghera, Gurdial Singh Oxford, GB 17 694
White, Steven Paul Oxford, GB 15 456

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