NOVEL ANTI-A2AP ANTIBODIES AND USES THEREOF

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United States of America Patent

APP PUB NO 20240166766A1
SERIAL NO

18525736

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to an isolated antibody or antigen-binding fragment thereof that binds to human A2AP. The isolated antibody or antigen-binding fragment according to the present invention i) cross-reacts with rabbit and/or cynomolgus A2AP, ii) does not inhibit human plasmin activity, and iii) increases plasmin mediated clot lysis in the presence of A2AP.

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Patent Owner(s)

Patent OwnerAddress
BAYER AKTIENGESELLSCHAFTKAISER-WILHELM-ALLEE 1 LEVERKUSEN 51373

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
FISCHER, Melanie Riedstadt, DE 4 10
GLUNZ, Julia Essen, DE 3 0
HEITMEIER, Stefan Wülfrath, DE 54 243
JÖRIßEN, Hannah Heiligenhaus, DE 13 77
SCHULENBURG, Cindy Zürich, CH 8 6
THIEL, Christoph Köln, DE 8 15
WEBER, Ernst Langenfeld, DE 27 65
WILMEN, Andreas Köln, DE 32 257

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