MONOCLONAL ANTIBODY AND USES THEREOF FOR THE TREATMENT AND DIAGNOSIS OF MULTIDRUG-RESISTANT PATHOGENIC BACTERIAL INFECTIONS

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United States of America Patent

APP PUB NO 20240166729A1
SERIAL NO

17996013

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Abstract

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The invention relates to human antibodies specific for Type III secretion system (T3SS), variants and biosimilars thereof. The human antibodies of the invention are specifically directed at the EspB protein. The preset disclosure further provides compositions and uses of the disclosed antibodies in treatment and diagnosis of MDR pathogenic bacterial infections.

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Patent Owner(s)

Patent OwnerAddress
RAMOT AT TEL-AVIV UNIVERSITY LTDPO BOX 39296 TEL AVIV 6139201

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
EVEN, Dan Tel Aviv, IL 2 5
GERSHBERG, Jenia Kiryat Gat, IL 1 0
HILLMAN, Yaron Tel Aviv, IL 1 0
LUSTIGER, Dan Tel Aviv, IL 1 0
SAL-MAN, Neta Lehavim, IL 2 4
WINE, Yariv Tel Aviv, IL 3 22

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