NOVEL RECOMBINANT STRAIN OF MYCOBACTERIUM SMEGMATIS AND USE OF SAME

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20240165216A1
SERIAL NO

18551954

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A recombinant Mycobacterium strain co-expressing MIF and IL-7, and a composition containing the strain as an active ingredient are disclosed. The strain and the composition are suitable for preventing or treating cancer. The strain induces a maximized anticancer immune response by stably expressing MIF and IL-7 through a mycobacteria-derived replicable plasmid, such as a pMyong2 shuttle vector. Accordingly, the strain and the composition may be usefully used as an efficient anticancer live vaccine composition that induces multiple cellular and humoral immune responses through single administration of the recombinant strain.

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Patent Owner(s)

Patent OwnerAddress
CLIPSBNC CO LTD(POLICE GONGJEHOE JALAM BILDING DOHWA-DONG)78 MAPO-DAERO MAPO-GU SEOUL 04168

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
AHN, Dong Ho Seoul, KR 21 163
JEONG, Hyein Seoul, KR 93 299
KIM, Bum-Joon Seoul, KR 21 108
KIM, Jae Hee Incheon, KR 38 402
SEO, Hyejun Seoul, KR 2 0

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