SMALL MOLECULE INHIBITORS OF SALT INDUCIBLE KINASES
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United States of America Patent
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Issued Date -
May 16, 2024
app pub date -
Jan 31, 2022
filing date -
Feb 1, 2021
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Abstract
Small molecule inhibitors of salt inducible kinases (SIKs) are provided. In particular, compounds of formula (I), and tautomers, stereoisomers, pharmaceutically acceptable salts and solvates thereof are provided. Also provided are pharmaceutical compositions containing the compounds, methods of preparing the compounds, and methods of using the compounds for inhibiting SIKs, such as SIK1 and SIK2, and methods of treating diseases mediated by SIKs.
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