NON-ACTIVATING ANTIBODY VARIANTS
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United States of America Patent
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Issued Date -
May 9, 2024
app pub date -
Mar 11, 2022
filing date -
Mar 12, 2021
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Abstract
Described herein are proteins comprising an Fc region or the like, such as monoclonal, bispecific and multispecific antibodies, wherein the Fc region has been modified to eliminate or strongly reduce Fc-mediated effector functions, while at the same time allow for good developability, for therapeutic purposes and where such effector functions are undesired.
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