METHODS AND COMPOSITIONS FOR TREATING AGITATION
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United States of America Patent
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Issued Date -
May 2, 2024
app pub date -
Feb 25, 2022
filing date -
Feb 26, 2021
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Abstract
The present disclosure relates to the treatment of agitation caused by noradrenergic hyperarousal in an agitated subject. The present disclosure provides oromucosal dosage forms comprising effective amounts of latrepirdine either alone or in combination with dexmedetomidine or pharmaceutically acceptable salts thereof and one or more pharmaceutically acceptable carriers and/excipients. Methods of their use are also provided. The present disclosure also provides a method of treating depression by administering oromucosally a therapeutically effective amount of dexmedetomidine alone or in combination with latrepirdine.
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