ENGINEERED TARGET SPECIFIC NUCLEASES

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United States of America Patent

APP PUB NO 20240132917A1
SERIAL NO

18493366

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Described herein are engineered nucleases comprising mutations in the cleavage domain (e.g., FokI or homologue thereof) and/or DNA binding domain (zinc finger protein, TALE, single guide RNA) such that on-target specificity is increased.

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Patent Owner(s)

Patent OwnerAddress
SANGAMO THERAPEUTICS INCRICHMOND CALIFORNIA 94804

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Miller, Jeffrey C Brisbane, US 104 3965
Rebar, Edward J Brisbane, US 90 4325

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