MECHANICALLY STABLE AND HIGH CELL DENSITY HONEYCOMB RETINAL SCAFFOLD DESIGN FOR TRANSPLANTATION THERAPY OF PHOTORECEPTOR CELLS AND RETINAL PIGMENT EPITHELIUM
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United States of America Patent
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Apr 25, 2024
app pub date -
Oct 11, 2020
filing date -
Oct 11, 2020
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Abstract
Photoreceptor scaffolds that can be used for transplantation of organized photoreceptor tissue, with or without retinal pigment epithelial cells, which may improve grafted cell survival, integration, and functional visual rescue are disclosed herein. The scaffolds include a cell support layer having at least one honeycomb-shaped reservoir fluidly connected to a plurality of through-holes and at least one cell in the at least one honeycomb-shaped reservoir.
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