TRANSAMINASE MUTANTS AND USES THEREOF

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United States of America Patent

APP PUB NO 20240124853A1
SERIAL NO

18264091

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Abstract

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Provided are transaminase mutants and uses thereof. The transaminase mutant is obtained by one or more amino acid mutations occurring in SEQ ID NO: 2 or is a mutant with a conserved amino acid mutation obtained by taking the sequence SEQ ID NO: 1 of a wild-type CvTA transaminase as a reference. Compared with wild-type transaminases, the catalytic activity of the mutant is improved to different degrees, so that the production efficiency of chiral amine compound synthesis may be improved.

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Patent Owner(s)

Patent OwnerAddress
ASYMCHEM LAB TIANJIN CO LTDNot Provided

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cao, Shan Tianjin, CN 4 0
Hong, Hao Morrisville, US 68 12
James, Gage Morrisville, US 32 9
Jiao, Xuecheng Tianjin, CN 17 0
Li, Xiang Tianjin, CN 1551 13938
Ma, Yulei Tianjin, CN 11 0
Mou, Huiyan Tianjin, CN 2 0
Sun, Kaihua Tianjin, CN 4 10
Wang, Zujian Tianjin, CN 5 0
Xiao, Yi Tianjin, CN 100 308
Zhang, Na Tianjin, CN 248 911
Zhao, Tong Tianjin, CN 226 3549

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